摘要
目的通过建立动脉硬化闭塞症(ASO)证候指数计量鉴别诊断表,对ASO3个常见中医证候进行计量诊断研究。方法采用流行病学横断面调查方法,收集179例ASO患者证候资料,用指数和法建立ASO证候指数计量鉴别诊断表,确定ASO证候的诊断临界值,在诊断临界值的基础上运用指数和法做定量鉴别诊断,并通过回代性检验和前瞻性检验对ASO证候指数计量鉴别诊断表的诊断效能进行评价。结果脉络寒凝证的诊断临界值为426;脉络血瘀证的诊断临界值为404,脉络瘀热证的诊断临界值为406。回代性和前瞻性检验的诊断效能评价中,3个证候的灵敏度、特异度均在90%以上,诊断符合率均在97%以上,误诊率、漏诊率均在6%以下。结论 ASO证候指数计量鉴别诊断表及指数和、指数和临界值法对其中医证候计量诊断具有良好的诊断效能与临床实用价值。
Objective To research the quantitative diagnosis of three common Chinese medicine syndromes in arteriosclerotic obliteration （ASO） through establishing the differential diagnosis table for syndrome index measurement. Methods The syn- dromes inlormation of 179 ASO patients was collected by epidemiological cross-sectional surveys. The differential diagnosis ta- ble for ASO syndrome index measurement was established with sum of index and the diagnostic threshold was determined. The sum of index was used to do the quantitative differential diagnosis on the basis of the diagnostic threshold. The efficiency of the differential diagnosis table for ASO syndrome index measurement was evaluated through backward-looking and forward-looking test. Results The diagnostic threshold of syndrome of cold congealing in the vessels and networks, syndrome of blood stasis in the vessels and networks and syndrome of stasis heat in the vessels and networks was 426, 404 and 406 respectively. The sensitivity and specificity of three syndromes were all above 90 %, the diagnosing coincident rate were all above 97 % and the misdiagnosing rate and missed diagnosing rate were all below 6%. Conclusion The differential diagnosis table for ASO syn- drome index measurement, sum of index and the critical value of sum of index is effective and functional for quantitative diagno- sis of Chinese medicine syndromes.
出处
《中医杂志》
CSCD
北大核心
2012年第17期1488-1491,共4页
Journal of Traditional Chinese Medicine
基金
首都医学发展科研基金资助项目(SF-2009-III-52)
北京中医药大学创新团队资助项目(2011CXTD-07)
关键词
动脉硬化闭塞症
计量诊断
指数和法
指数和临界值法
arteriosclerosis obliterans
quantitative diagnosis
sum of index
the critical value of sum of index
