摘要
目的研究跑步运动对降低高脂血症的作用及其强度,为治疗高脂血症提供一种非药物治疗的方便可行的方法。方法通过小鼠对照实验,分为普通组、药物对照组(注射降脂药物)、高脂模型组及高脂跑步组四组对照。对高脂跑步组进行跑步运动,药物对照组每天定量注射药物,其余正常喂养并每天灌胃,3周后测定血清胆固醇、三酰甘油、高密度脂蛋白指标,得到数据作统计分析。结果高脂模型组即不运动的小鼠的血清胆固醇(2.63±0.31)mmol/L、三酰甘油(2.14±0.61)mmol/L均高于跑步组血清胆固醇(1.71±0.49)mmol/L、三酰甘油(1.71±0.49)mmol/L和药物对照组血清胆固醇(1.61±0.22)mmol/L、三酰甘油(1.63±0.38)mmol/L,跑步组血清胆固醇(1.71±0.49)mmol/L、三酰甘油(1.71±0.49)mmol/L与药物对照组血清胆固醇(1.61±0.22)mmol/L、三酰甘油(1.63±0.38)mmol/L相近且接近普通组血清胆固醇(2.30±0.23)mmol/L、三酰甘油(1.51±0.32)mmol/L。结论跑步运动在高强度情况下对降脂有明显效果,与药物相比无显著性差异;中度情况下效果不明显,因此适当的运动能有效的预防及治疗高脂血症。
Objective To observe the effect and intensity of jogging exercise on reducing hyperlipoidemia so as to provide a convenient and feasible non-pharmacotherapy way to treat hyperlipoidemia.Methods Mice were taken for the control experiment which were divided in- to for groups ： common group, drug control group（with lipid-lowering drug injection）, hyperlipemia model group, and hyperlipemia jogging ex- ercise group.The hyperlipemia jogging exercise group had jogging exercise, the drug control group had regular daily lipid-lowering drug injec- tion, the other groups had normal feeding and daily intragastric administration.Three weeks later serum cholesterol, triacylglycerol, high-densi- ty lipoprotein were measured and analyzed.Results Serum cholesterol（2.63 ± 0.31）mmol/L and triacylglycerol（2.14 ± 0.61）mmol/L of the hyperlipemia model group were both higher than those of the jogging exercise group with cholesterol（1.71 ± 0.49）mmol/L and triacylglyc- erol（1.71 ± 0.49）mmol/L and the drug control group with cholesterol（1.61 ± 0.22）mmol/L and triacylglycerol（1.63 ± 0.38）mmol/L. Serum cholesterol （1.71 ± 0.49）mmol/L and triacylglycerol （1.71 ± 0.49）mmol/L of the jogging exercise group,together with Serum cholesterol（1.61 ± 0.22）mmol/L and triacylglycerol（1.63 ± 0.38）mmol/L of the drug control group, were close to those of the common group with Serum cholesterol（2.30 ± 0.23）mmol/L and triacylglycerol（1.51 ± 0.32）mmol/L.Conclusion Jogging exercise with high in- tensity can have obvious effects on lipid lowering without much difference from those by taking drugs, while moderate jogging exercise doesn＇t have clear effects. So proper jogging exercise can effectively prevent and treat hyperlipoidemia.
出处
《中国疗养医学》
2012年第8期685-689,共5页
Chinese Journal of Convalescent Medicine
关键词
高脂血症
血清
胆固醇
Hyperlipoidemia
Serum
Cholesterol
