摘要
目的 :研究心脏不停跳心内直视先心纠治术对心肌肌钙蛋白 (c Tn- T)的影响及意义。方法 :检测 16例体外循环心脏不停跳心内直视先心纠治术治疗患者术前、术中及术后血清 c Tn- T及肌酸磷酸激酶同功酶 (CK- MB) ,并进行对比分析。结果 :血清 c Tn- T明显增高 ,于停机时达到最高峰 ,并持续高于术前水平至术后 2周。CK- MB于术后 2 h达最高峰 ,术后 1周即恢复至术前水平。结论 :体外循环心脏不停跳先心纠治术中 ,血清 c Tn- T可用于评价围手术期心肌细胞损伤和心肌保护效果的指标 ,其敏感性、特异性及持续时间优于 CK- MB。
Objective:To study the effects and significance on cardiac troponin T(cTn T) during cardiac surgery with compulmonary bypass (CPB) in patients with congenital heart disease (CHD) Methods:During the perioperative term,the serum concentration of cTn T and creatine kinase MB(CK MB) were measured in 16 patients with CHD who had undergone cardiac surgery with CPB Results:cTn T came to its peak while stopping CPB and kept a higher level than preoperative level for two weeks postoperatively,however,CK MB reached its peak in 24 hours post operative course and returned to its preoperative level for 7 days postoperatively Conclusion:cTn T may be an useful and valuable indicator in evaluating the degree of myocardial cell damage and myocardial protection,and its censitivity,specificity and lasting time are better than cardiac erzymes
出处
《广西医科大学学报》
CAS
2000年第1期55-56,共2页
Journal of Guangxi Medical University
关键词
体外循环
心肌肌钙蛋白T
CK-MB
心内直视术
compulmonary bypass
corgenital heart disease
cardiac troponin T
creative kinase MB
