摘要
目的：探讨心脏不停跳心内直视术甲状腺功能改变及意义。方法：用放射免疫分析法测定２７例心脏不停跳心内直视术的成人及儿童先心病患者术前、术中及术后甲状腺功能的改变。结果：①儿童组及成人组术中及术后血清ＴＴ３、ＦＴ３、ＴＴ４、ＦＴ４浓度低于术前，ｒＴ３明显增高，ＴＳＨ不升；②儿童组血清ＴＴ４、ＦＴ４最低值出现早于成人组；③预后不良患者血清ＴＴ３、ＴＴ４明显低于均值。结论：①心脏不停跳心内直视术治疗的先心患者术后出现“正常甲状腺病态综合征”；②根据激素的变化水平可预测患者预后；③甲状腺激素替代疗法可能有益于心肌保护。
Objective:To study the function of thyroid during and after cardiac surgery on beating heart Methods:In this experiment thyroid function was investigated in 27 patients of congenital cardiovascular diseases (CHD) of adults and children undergoing cardiac surgery on beating heart before,during and after operation Results:①A fall occured in TT 3,FT 3,TT 4,FT 4 and “blunted response” of TSH during and after operation in adults group and children group,however,concentration of rT 3 increased obviously ②At the same time,the minimal concentration of TT 4,FT 4 in children group appeared earlier than adults group ③In patients who had a particularly difficult postoperative course,TT 3,TT 4 remained in low level and no increase was found Conclusions:①The “euthyroid sick syndrome” occured in patients undergoing cardiac surgery on beating heart ②The change in thyroid function after CPB would help us evaluate the course of recovery ③Thyroid hormone replacement therapy could well have been beneficial to myocardial protetion
出处
《广西医科大学学报》
CAS
1999年第2期165-167,共3页
Journal of Guangxi Medical University
关键词
心脏不停跳
甲状腺功能
先心病
心内直视术
beating heart
thyroid function
congential cardiovas cular diseases
