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高危型人乳头瘤病毒检测对196例宫颈上皮内瘤变的诊断价值 被引量：1

The value of detecting high risk type human papillomavirus DNA in diagnosing of 196 cases of cervical intraepithelial neoplasia
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摘要 [目的]明确高危型人乳头瘤病毒基因(HR-HPV DNA)检测在诊断宫颈上皮内瘤变(CIN)中的意义.[方法]选取196例进行HPV DNA检测并经组织学诊断为CIN的患者资料进行分析.[结果]HR-HPV DNA在CINⅠ,CINⅡ,CINⅢ级中的阳性表达率分别为88.63%(39/44),90.00%(36/40),93.75%(105/112),三者之间差异具有统计学意义(P<0.05);且HR-HPV的阳性表达率随着宫颈病变的级别上升呈逐渐增高的趋势.[结论]HR-HPV DNA检测对CIN诊断有重要价值. OBJECTIVE To determine the significance of detecting high risk type human papillomavirus（HR-HPV） DNA in diagnose of cervical intraepithelial neoplasia（CIN）.METHODS 196 cases were selected from hospital to detect the HPV DNA,and the data of patients with CIN were analyzed.RESULTS HR-HPV DNA positive rates in CINⅠ,CINⅡ,CINⅢ were 88.63%（39/44）,90.00%（36/40） and 93.75%（105/112）,respectively,and the difference was statistical significance in 3 groups（P〈0.05）.And the greater risk of cervical lesions were,the higher HR-HPV DNA positive rates were.CONCLUSION HR-HPV detection plays an important role in diagnosis of CIN.
作者 孙波 邱雪杉
机构地区 中国医科大学基础医学院病理学教研室
出处 《延边大学医学学报》 CAS 2012年第2期139-141,共3页 Journal of Medical Science Yanbian University
关键词 宫颈上皮内瘤样病变 乳头状瘤病毒 人 诊断技术 妇产科 cervical intraepithelial neoplasia papillomavirus,human diagnostic techniques,obstetrical and gynecological
分类号 R365 [医药卫生—病理学]
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二级参考文献87

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共引文献33

同被引文献23

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延边大学医学学报
2012年 第2期

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