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来曲唑与克罗米芬治疗多囊卵巢综合征促排卵疗效分析 被引量:13

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摘要 目的:应用来曲唑与克罗米芬治疗多囊卵巢综合征排卵障碍患者,比较来曲唑与克罗米芬对卵泡发育、排卵及子宫内膜增长的影响。方法:选择本院门诊2009年12月-2011年12月多囊卵巢综合征排卵障碍患者50例,随机分两组,接受来曲唑和克罗米芬药物治疗,hCG注射日比较两组患者的成熟卵泡发育率、排卵率、子宫内膜厚度、妊娠率的情况。结果:克罗米酚组出现优势卵泡20例(80%),来曲唑组16例(64%),两组比较,差异不具有统计学意义(P>0.05)。克罗米酚组排卵11例(55%),来曲唑组13例(81.25%),两组比较差异无统计学意义(P>0.05);hCG注射日子宫内膜厚度,克罗米酚组(9.01±1.97)mm,来曲唑组(7.86±1.22)mm,两组比较,差异有统计学意义(P<0.05)。结论:在促排卵过程中,来曲唑对成熟卵泡增长活性较高,临床促排卵效果较克罗米芬优越,且对子宫内膜厚度影响较轻。
出处 《中国医学创新》 CAS 2012年第21期139-140,共2页 Medical Innovation of China
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参考文献4

  • 1常秀峰,张建平,张敏,余裕炉.来曲唑促排卵研究进展[J].国际生殖健康/计划生育杂志,2009,28(1):20-23. 被引量:19
  • 2Mitwally M F, Casper R F.Use of an aromatase inhibitor for inducting of ovulation in patients with an inadequate response to clomipheng citrate[J]. Fertil Steril, 2001, 75(2) : 305-309. 被引量:1
  • 3李艳萍,张琼,周庆娥,刘冬娥,刘能辉,邓利,陈仙花.来曲唑促排卵治疗的临床观察[J].生殖医学杂志,2006,15(3):150-152. 被引量:14
  • 4A1-Fozan H, AL-Khadouri M, Tan S L, et al.A randomizedtrial of Letrozole veraus clomiphene ejtrate in Women undergoing Superovulation[J].FertilSteril, 2004, 82(6):1561-1563. 被引量:1

二级参考文献10

  • 1Lamb HM,Adkins JC.Letrozole:a review of its use in postmenopausal women with advanced breast cancer[J].Drugs,1998,56(6):1125-1140. 被引量:1
  • 2Mitwally MFM,Casper RF.The use of an aromatase inhibitor for induction for ovulation in cases of clomiphene citrate failure[J].Hum Reprod,2000,15(Abstract BK1):0-178. 被引量:1
  • 3Kilic-Okman T,Kucuk M,Altaner S.Comparison of the effects of letrozole and clomiphene citrate on ovarian follicles,endometrium and hormone levels in the rat[J].Fertil Steril,2003,80(6):1330-1332. 被引量:1
  • 4Mitwdly MF,Casper RF.Use of an aromatase inhibitor for induction of ovulation in patients with an inadequate response to clomiphene citrate[J].Fertil Steril,2001,75 (2):305-309. 被引量:1
  • 5Fisher SA,Reid RL,Van Vugt DA,et al.A randomized double-blind comparison of the effects of clomiphene citrate and the aromatase inhibitor letrozole on ovulatory function in normal women[J].Fertil Steril,2002,78(2):280-285. 被引量:1
  • 6罗丽兰主编.不孕与不育[M].第2版.北京:人民卫生出版社,1999.44-185. 被引量:1
  • 7Al-Fozan H,Al-Khadouri M,Tan SL,et al.A randomized trial of letrozole versus clomiphene citrate in women undergoing superovulation[J].Fertil Steril,2004,82 (6):1561-1563. 被引量:1
  • 8Mitwdly MF,Casper RF.Use of an aromatase inhibitor for induction of ovulation in patients with an inadequate response to clomiphene citrate[J].Fertil Steril,2001,75(2):305-309. 被引量:1
  • 9Healey S,Tan SL,Biljan MM,et al.Letrozole and gonadotropins:what is the ideal patient protocol?[J].Fertil Steril,2003,80(6):1339. 被引量:1
  • 10Al-Fadhli R.,Sylvestre C.,Buckett W.,T. Tulandi,张旸.两种不同剂量来曲唑行超排卵的随机试验[J].世界核心医学期刊文摘(妇产科学分册),2006,0(4):32-32. 被引量:2

共引文献30

同被引文献129

  • 1时妍嫣.达英-35联合二甲双胍治疗克罗米芬不敏感型多囊卵巢综合征的疗效观察[J].河南外科学杂志,2010,16(3):26-28. 被引量:9
  • 2黎平,阮晓红,郭江华,陈晓燕,邓爱民.来曲唑与克罗米芬诱导排卵疗效比较[J].中国医药,2007,2(6):364-366. 被引量:6
  • 3任凤岩,李一宁,王丹波,张淑兰.血管生成与多囊卵巢综合征发病机制的关系[J].中国全科医学,2007,10(13):1121-1123. 被引量:2
  • 4任长安.耐克罗米芬的多囊卵巢综合征治疗研究进展[J].中国性科学,2007,16(11):32-36. 被引量:2
  • 5Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Work-shop Group.Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome.Fertil Steril,2004,81(1):19-25. 被引量:1
  • 6Abd Elgafor I.Efficacy of combined metformin-letrozole in comparison with bilateral ovarian drilling in clomiphene-resistant infertile women with polycystic ovarian syndrome.Arch Gynecol Obstet,2013,288(1):119-123. 被引量:1
  • 7Atay V,Cam C,Muhcu M.et al.Comparison of letrozole and clomiphene citrate in women with Polycystic ovaries undergoing ovarian stimulation.J Int Med Res,2006,34(1):73-76. 被引量:1
  • 8Coviello A D,Legro R S,Dunaif A.Adolescent girls with polycystic ovary syndrome have an increased risk of the metabolic syndrome associated with increasing androgen levels independent of obesity and insulin resistance[J].J Clin Endocrinol Metab,2012,91(2):492-497. 被引量:1
  • 9Banerjee Ray P,Ray A,Chakraborti PS.Comparison of efficacy of letrozole and clomiphene citrate in ovulation induction in Indian women with polycystic ovarian syndrome[J].Arch Gynecol Obstet,2012,285(3):873-877. 被引量:1
  • 10FABREGUES F, IRAOLA A, CASALS G, et al. Evaluation oftwo doses of recombinant human luteinizing hormone supplementa-tion in down - regulated women of advanced reproductive age un-dergoing follicular stimulation for IVF : a randomized clinical study[J]. Eur J Obstet Gynecol Reprod Biol, 2011,158(1) : 56-61. 被引量:1

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