摘要
目的了解健康人群接种甲型H1N1流感(甲流)疫苗后的流行病学保护效果。方法采用描述流行病学、队列研究方法对2 116名接种和2 762名未接种甲流疫苗的师生随访1年,观察其流感样病例发病情况。结果接种组流感样病例发病率3.2%,未接种组发病率4.5%,差异有统计学意义(χ2=4.869,P=0.027),疫苗保护率为28.9%。OR值随接种率升高而降低。季节性流感疫苗并不是保护因素。结论甲流疫苗对包括甲流在内的流感样病例有较好的流行病学保护效果。
Objective To evaluate the epidemiological effects of influenza A （ H1N1 ） vaccine on health population. Method Descriptive epidemiology and cohort study design were used. 2116 students and teachers who had receive influenza A （H1N1） vaccine （immunized group） and 2762 who had not （unimmunized group） been followed - up one year to observe whether the influenza - like illness was occurred. Results The influen- za - like illness incidence rate of the immunized group was 3.2%, and that of unimmunized group was 4. 5%. There were statistical significance between two groups （X^2 = 4. 869, P = 0. 027 ） and the protective rate was 28.9%. The higher the immunization rate was, the lower the OR value was. Seasonality influenza vaccine wasnt the protective factor. Conclusions Influenza A （H1N1） vaccine had good epidemiological protective effects on influenzalike illness including influenza A （H1N1 ） .
出处
《医学动物防制》
2012年第7期769-771,共3页
Journal of Medical Pest Control
关键词
甲型H1N1流感
疫苗
保护效果
流感样病例
Influenza A （ H1N1 ）
Vaccine
Protective effects
Influenza - like illness
