摘要
目的:观察复方甘草酸苷联合曲安奈德皮损内注射和液氮冷冻治疗斑秃的临床疗效。方法:将120例斑秃患者随机分为治疗组(n=60)和对照组(n=60),全部给予曲安奈德混悬液皮损内注射和液氮冷冻治疗,治疗组加口服复方甘草酸苷片。总疗程为8周,每2周观察和记录皮损内头发生长情况和不良反应,共观察12周。结果:治疗组的痊愈率(70.00%)和有效率(90.00%)均优于对照组,治疗4周后治疗组的有效率一直优于对照组,且差异都有统计学意义(P<0.05)。结论:复方甘草酸苷联合曲安奈德皮损内注射和液氮冷冻治疗斑秃,疗效显著且疗程短,安全性高,值得临床推广应用。
Objective To observe the clinical efficacy of compound glycyrrhizin combined with intralesional injection with triamcinolone and cryotherapy with liquid nitrogen in the treatment of alopecia areata.Methods 120 patients with alopecia areata were randomly divided into treatment group（n = 60） and control group（n = 60）.All patients were accepted intralesional injection with triamcinolone suspension and cryotherapy with liquid nitrogen.The patients of treatment group were added to take compound glycyrrhizin orally.The total period of treatment was 8 weeks.The hair growth of lesions and adverse reaction was observed and recorded every 2 weeks,for 12 weeks in all.Results The cure rate（70.00%）and effective rate（90.00%）of treatment group was higher than that of control group.The effective rate of treatment group was continuously higher than that of control group after treating for 4 weeks.All the difference had statistical significance（P 0.05）.Conclusion For treating alopecia areata,compound glycyrrhizin combined with intralesional injection with triamcinolone and cryotherapy with liquid nitrogen has the advantages of evident efficacy,short treating period and high safety.It is worthy of clinical popular application.
出处
《实用医学杂志》
CAS
北大核心
2012年第14期2429-2431,共3页
The Journal of Practical Medicine
关键词
斑秃
复方甘草酸苷
曲安奈德
冷冻疗法
Alopecia areata
Compound glycyrrhizin
Triamcinolone
Cryotherapy
