摘要
目的:探讨一种简便安全的新生儿溶血病换血治疗方法。方法:采用肱动脉、头皮静脉为输入、出通道,对35例新生儿溶血病患儿实施双通道同步部分换血治疗,监测换血前后血常规、血气、血生化、凝血四项、肝肾功能、黄疸常规。结果:全部病例换血过程中,胆红素迅速降低,贫血得以纠正。换血前后电解质、血糖、脉搏、呼吸频率、体温无明显变化。结论:外周动静脉同步部分换血疗法治疗新生儿溶血可满足临床换血治疗的要求,并且方便安全。外周动静脉同步部分换血疗法疗效好,操作简单,不良反应少。
Objective ：To evafvate the superior of the persistent exchange transfusion by peripheral vasculour and spread this method. Method： There are 35 cases applied partial peripheral arteria and vein synchronization exchange transfusion. At the same time we also monitor variance between the before and after in the exchange transfusion therapy to the blood routine test, blood gas analysis, blood biochemistry, blood conagulation four items（ PT, INR, Fib, APTT） , liver and kidney function, blood jaundice routine test. Result ：The blood serum bilirubin is lower. Comparison to protreatment, there is no difference in blood biochemistry, blood sugar, heart rate, breath rate and temperature, ect. Conclusion ： Partial exchange transfusion by peripheral vasculour is better than exchange transfusion by umbilical wein. It is simple, safe practicable and effective with few complications for neonates, and it maybe applied in basic hospital.
关键词
新生儿溶血
换血
外周动静脉同步部分
Hemolytic disease of neonates
Exchange transfnsion
Partial exchange transfugion by peripheraivasculour
