摘要
近年来,有机小分子催化剂已成为不对称合成研究领域的热点.脯氨酸在诸多不对称反应中显示出的良好的催化选择性,由此对脯氨酸的结构进行修饰和改造也引起人们的兴趣,以期得到催化性能更优越的催化剂。本文将脯氨酸衍生物分为十类,以其类型为线索综述了其在不对称催化反应中的研究进展。
The small organic molecules catalyst was a hotspot in asymmetric synthesis. Due to the excellent enantiselectivity of proline in many asymmetric reactions, people showed great interest in the modification of it, which aimed to get better organocatalysts. Proline derivatives were divided into ten kinds and reviewed the progression in asymmetric reactions according to these types in this paper.
出处
《药学实践杂志》
CAS
2012年第1期19-24,41,共7页
Journal of Pharmaceutical Practice
关键词
脯氨酸衍生物
不对称合成
对映选择性
有机催化
proline derivatives
asymmetric synthesis
enantioselectivity
organocatalysis
