摘要
目的评价针灸治疗围绝经期睡眠障碍的临床有效性。方法搜集针灸治疗围绝经期睡眠障碍的临床随机对照研究,同时应用计算机和手工检索相关中英文数据库,使用Cochrane Handbook推荐的质量评价方法对文献进行质量评价,采用RevMan5.1.2软件进行统计分析。结果本系统评价纳入随机对照研究11个,共858例患者。有效率针灸疗法与药物对照比较,差异有统计学意义[OR=5.99,95%CI(2.32,15.49),P=0.0002]。亚组分析表明:针刺与中药对照比较,差异无统计学意义[MD=2.34,95%CI(0.23,23.78),P=0.47];而针刺与西药、特殊针法与中西药物对照,差异均有统计学意义。在提高血清雌二醇水平方面,针灸疗法与药物比较,差异有统计学意义[OR=33.69,95%CI(29.87,37.50),P<0.000 01]。在提高睡眠质量方面,针刺与药物对照,差异无统计学意义[MD=-0.62,95%CI(-2.75,1.51),P=0.57]。结论针灸对围绝经期睡眠障碍有一定疗效。
Objective To assess the efficacy of acupuncture treatment on menopause sleep disorders.Methods Collect randomized controlled clinical trial involving acupuncture for menopause sleep disorders,retrieve Chinese and English relevant database by computer and manual searching,then evaluate the quality of the literature according to Cochrane Handbook recommended quality assessment method,and statistically analyze the data using software RevMan5.1.2.Results The systematic review included eleven randomized controlled study with a total of 858 cases.Meta-analysis derived：the difference in efficiency,the acupuncture treatment compared with drug control,was statistically significant [OR=5.99,95%CI（2.32,15.49）,P=0.000 2].Sub-group analysis showed that：between acupuncture and herb control,the difference was not statistically significant [OR=2.34,95%CI（0.23,23.78）,P=0.47].While between acupuncture and western medicine control,special acupuncture and Chinese and Western medicine control,the differences were both statistically significant.In increasing serum E2 levels,acupuncture compared with drug therapy,the difference was statistically significant [MD=33.69,95% CI（29.87,37.50）,P〈0.000 01].In increasing PSQI index,acupuncture compared with drug therapy,the difference was not statistically significant [MD=-0.62,95%CI（-2.75,1.51）,P=0.57].Conclusion Acupuncture has some effect on menopause sleep disorders
出处
《中国中医药信息杂志》
CAS
CSCD
2012年第8期24-26,共3页
Chinese Journal of Information on Traditional Chinese Medicine
