摘要
采用粉末冶金法制备了纳米羟基磷灰石(nHA)钛基生物医用复合材料,借助XRD、EDS、SEM、压缩弹性模量试验以及生物矿化过程和细胞活性分析,研究了10%的nHA对钛基生物医用材料结构及性能的影响。结果表明,钛基生物医用复合材料的主晶相仍为Ti,同时也有少量的Ti2O、Ti5P3和CaTiO3化合物,这些化合物分布于Ti晶粒的周围;添加nHA改变了钛生物材料的高温烧结性能,材料晶粒间孔隙明显增多;添加nHA后的钛基复合材料,压缩弹性模量仅为纯Ti试样的一半左右,接近人体皮质骨的压缩弹性模量;添加nHA后的钛基复合材料具有更好的生物活性。
The nHA Ti-based biomedical composites were prepared by powder metallurgy,and effects of nano-hydroxyapatite on microstructure and performance of Ti-based biomaterials prepared were investigated by XRD（X-ray diffraction）,EDS（energy dispersive spectrometer）,SEM（scanning electron microscope） and compression elastic modulus testing.The results show that the major phase is Ti phase,and Ti2O,Ti5P3,and CaTiO3 are generated and distributed in the around of Ti phase.The addition of nano-hydroxyapatite can change the sintering property and increase the porosity of the materials prepared.Compared to pure Ti specimen,the compressive elastic modulus of nano-hydroxyapatite/Ti biomaterial is reduced by a half,which is near to the human cortical bone’s.The biomineralization process and cell activity analysis also show that the nano-hydroxyapatite /Ti biomaterial has better biological activity,and it is more suitable for human hard tissue replacement and repairment.
出处
《特种铸造及有色合金》
CAS
CSCD
北大核心
2012年第7期650-653,共4页
Special Casting & Nonferrous Alloys
基金
广东省科技计划项目(2010B010800024
2008B010600044)
关键词
钛基生物材料
纳米羟基磷灰石
结构和性能
Ti-Based Biomaterial
Nano-Hydroxyapatite
Microstructure and Performance
