摘要
研究急性坏死性胰腺炎 (ANP )血液流变学改变及其在病情演进中的作用。方法 检测ANP大鼠的血液流变学指标 ,红细胞脆性及胰腺病理学检查。结果 ANP大鼠全血粘度 ,血浆粘度 ,红细胞压积均显著升高 ,红细胞脆性增加 ;纤维蛋白原降低。结论 ANP时 ,出现显著血液流变学改变 ,后者可能是胰腺进行性坏死 。
Objective To study the hemorrheologic alternation in acute necrotizing pancreatitis(ANP) and its effect in deterioating of ANP. Methods Blood samples were obtained from ANP rats for hemorrheologic examination and erythrocyte osmotic fragility test. Pancreatic tissue was obtained for pathological study. Results Blood viscosity, plasma viscosity, hematocrit, erythrocyte osmotic fragility were significantly elevated, while erythrocyte sedimentation rate and fibrinogen were decreased significantly in ANP rats compared with sham operation group. Conclusions In ANP rats, hemorrheology is altered significantly, which may be one of the important factors in deterioraton the disease.
出处
《中国普通外科杂志》
CAS
CSCD
2000年第3期225-227,共3页
China Journal of General Surgery
关键词
胰腺炎
病理生理学
血液汉变学
急性病
PANCREATITIS/physiopathol
HEMORRHEOLOGY
ACUTE DISEASE
PANCREATITIS/pathol
NECROSIS
