摘要
目的比较角膜缘干细胞移植和羊膜移植对复发性翼状胬肉的疗效。方法将81例（94只眼）复发性翼状胬肉患者随机分成A、B组：A组45例（48只眼）行翼状胬肉切除联合自体角膜缘干细胞移植术；B组36例（46只眼）行翼状胬肉切除术联合羊膜移植术。随诊1．5年，观察两组患者的角膜修复时间、复发率及并发症。结果A组3例患者（3只眼）翼状胬肉复发，复发率为6．3％；B组7例患者（10只眼）翼状胬肉复发，复发率为21．7％，两组比较，差异有统计学意义（X^2=4．729，P=0．03）。结论角膜缘干细胞移植术与羊膜移植术相比能明显的降低复发率，减少角膜修复时间，是治疗复发性翼状胬肉的好方法。
Objective To evaluate the therapeutic effects of limbal epithelial autograft and amni- otic membrane grafting on recurrent pterygium. Methods There were 81 patients （94 eyes） with first recurrent pterygium and they were allocated two groups： excision of pteryginm with limbal epi- thelial autograft transplantation surgery （group A, 45 cases with 48 eyes） and excision of pterygium with amniotic membrane grafting （group B, 36 cases with 46 eyes）, the post-operative follow-up peri- ods ranged 18 months to analyze the recurrent rate, the repair time of epithelium and complication. Results In the eyes follow-up 3 of 48 eyes （6.3%） in group A and 10 of 46 eyes （21.7%） in group B were recurred. There was difference in recurrent rate between the two groups （X2=4.729, P = 0.03）. Conclusions Limbal epithelial autograt transplantation can reduce the recurrence and make the repair time of epithelium lower. It is a reasonable therapeutic method for the treatment of recurrent prerygium than amniotic membrane grafting.
出处
《中国实用眼科杂志》
CSCD
北大核心
2012年第7期831-833,共3页
Chinese Journal of Practical Ophthalmology
关键词
复发性翼状胬肉
干细胞
移植
羊膜移植
Recurrent pterygium
Stem cell
Transplantation
Amniotic membrane
