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生物补片材料在盆底功能重建中的应用 被引量:5

Biological patch materials in pelvic functional reconstruction
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摘要 背景:盆底结构缺陷、损伤以及功能障碍可以导致盆腔脏器膨出,外科治疗是主要方法,随着盆底缺陷修复和功能重建技术的发展,生物补片材料成为重要的盆底筋膜组织替代物,在盆底功能重建中的应用越来越广泛。目的:对生物补片材料在盆底功能重建应用研究的文献资料趋势进行多层次探讨分析。方法:以电子检索方式对万方数据库2007-01/2011-12有关生物补片材料在盆底功能重建应用研究的文献进行分析,采用检索词为"补片(patch);盆底功能重建(pelvic functional reconstruction);盆腔脏器膨出(pelvic organ bulging);生物材料(biomaterial)",运用数据库中自带的分析功能和Excel软件绘制图表的功能,分析文献年度命中数、出版时间及数量、学科类别、基金资助、博硕士学位论文、会议论文和专利信息,以及不同补片材料临床应用效果比较。结果与结论:在万方数据库学术期刊收录的2007/2011文献中,共检索到30篇相关文献。5年来补片材料研究文献的年度命中数处于明显的上升趋势,生物补片材料在盆底功能重建应用研究的文献量处于平稳状态;《中国组织工程研究与临床康复》杂志在生物补片材料盆底功能重建应用研究领域发稿较多;文献的关键词主要有盆腔脏器脱垂、聚丙烯补片和生物相容性,可见生物补片材料在盆腔脏器脱垂疾病中的应用较多,以聚丙烯补片材料的研究为主,突出研究材料的生物相容性。通过文献计量学方法对万方数据库关于生物补片材料在盆底功能重建应用研究的文献分析,为中国从事生物补片材料在盆腔脏器膨出基础研究和临床医务工作者进一步确定科研思路提供有价值的参考。 BACKGROUND: Surgical treatment is the main method for treating pelvic organ prolapse resulting from structure defect, damage of pelvic floor, or pelvic floor dysfunction. With the development of technology in repair and functional reconstruction of pelvic floor defects, as an important pelvic fascia tissue substitute, biological patch materials are widely used in the pelvic floor reconstruction. OBJECTIVE: To explore the literature data trends in the study of biological patch materials in pelvic functional reconstruction METHODS: A search of articles related to biological patch materials in pelvic functional reconstruction was performed in Wanfang database, with key words of "patch, pelvic functional reconstruction, pelvic organ bulging, biomaterial", from 2007 01 to 2011 12. The distribution characteristics of research trends were described by using database analysis capabilities and Excel charting functions. The literatures were analyzed by annual number of hits, published year, literature number, subject categories, funds, as well as to compare the clinical effect of different patch materials in PhD thesis, master's degree papers, conference papers, and patented technology in Wanfang database. RESULTS AND CONCLUSION: A total of 30 research literatures were retrieved in Wanfang database from 2007 to 2011 The annual number of hits addressing literature research in patch materials showed a clear upward trend in recent 5 years, and the number of papers related to biological patch materials in pelvic functional reconstruction was in a steady state. Journal of Clinical Rehabilitative Tissue Engineering Research published more literatures than other journals. The pelvic organ prolapsed, polypropylene patch and biocompatibility are widely studied in the literatures addressing the application of biological patch materials in pelvic organ prolapse, and polypropylene patch material is the focus of the study, which highlights the biocompatibility of materials. The bibliometric analysis on biological patch ma
作者 王芳
出处 《中国组织工程研究》 CAS CSCD 2012年第25期4719-4726,共8页 Chinese Journal of Tissue Engineering Research
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