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妊娠合并静脉血栓栓塞性疾病诊治特点研究 被引量:4

Characteristic of Diagnosis and Treatment of Pregnancy Complicated With Venous Thromboembolic Disease Research
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摘要 目的:探讨妊娠合并静脉血栓栓塞性疾病诊治特点。方法:对15例妊娠合并静脉血栓栓塞性疾病患者的发病特点、诊疗方法进行分析。结果:15例妊娠合并静脉血栓患者,14例用低分子肝素治疗,其中1例流产,1例发生严重肺栓塞后经大剂量尿激酶治疗后行剖宫产,1例并发胎盘早剥,放置可回收下肢静脉滤器,1例患者同时并发深静脉血栓和肺栓塞,放置下肢静脉滤器后行剖宫产术,1例要求结束妊娠,放置下肢静脉滤器后行人工流产术;所有患者经治疗后临床症状得到缓解,15d后患肢肿胀、疼痛消失,患肢周径与健侧差距缩小到(1.9±0.4)cm。新生儿均正常健康,新生儿出生10min Apgar评分均>8分。所有患者在治疗期间均无出血并发症,无死亡。结论:治疗妊娠合并静脉血栓栓塞性疾病首选低分子肝素(或肝素),非必要情况下不宜用溶栓治疗。应用下肢静脉滤器要把握适应证,必要时放置可回收下肢静脉滤器,防止发生严重性肺栓塞。 Objective:To investigate the characteristics of diagnosis and treatment of pregnancy complicated with venous thromboembolic disease.Methods:IS cases of pregnancy complicated with venous thromboemholic disease characteristics, diagnosis and treatment methods for analysis. Results:IS cases of pregnancy complicated with venous thrombosis, 14 cases with low molecular heparin in the treatment of 1 cases of abortion, among them, 1 case of severe pulmonary embolism after large dose urokinase in the treatment of patients after cesarean section, 1 case of placental abruption, placing recyclable venous filter, 1 patients complicated with deep venous thrombosis and pulmonary embolism, placed venous filter after cesarean section, 1 cases of the end of pregnancy, placed venous filter after artificial abortion ; after treatment all patients clinical symptoms have been alleviated, 15 d affected limb swelling, pain, limb circumference than the uninjured side gap to (1.9+0.4)cm.Newborns were healthy, newborn 10 minute Apgar score 〉8 points.All patients during the treatment period are no bleeding complications, no death.Conclusion:Treatment of pregnancy complicated with venous thromboembolic disease preferred low molecular weight heparin or heparin therapy, unnecessary cases should not use of thrombolytic therapy.Application of lower extremity venous filter to grasp the indications, if necessary placing recyclable venous filter to prevent the occurrence of serious pulmonary embolism.
作者 王晓萍
出处 《中国医学创新》 CAS 2012年第18期119-121,共3页 Medical Innovation of China
关键词 静脉血栓栓塞性疾病 妊娠期深静脉血栓 肺栓塞 Venous thromhoemholie disease in pregnancy Deep venous thrombosis Pulmonary embolism
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