摘要
胰腺癌是一种常见的恶性消化道肿瘤，近年来其发病率有明显上升的趋势。由于早期症状不明显，临床确诊的胰腺癌患者多已处于中晚期，大多失去手术治疗机会，预后极差。因此，提高胰腺癌的早期诊断率非常重要。近年来，蛋白质组学发展迅速，广泛应用于临床研究，特别是胰腺癌肿瘤标志物的研究。本文就蛋白质组学技术在胰腺癌血清、胰液、胰腺癌组织细胞和胰腺癌细胞中的应用作一综述。
Pancreatic cancer is a commonly malignant gastrointestinal tumor with an significantly increasing incidence. Those patients without nonspecific symptoms at early stage had mostly lost the opportunity of surgical therapy when pancreatic cancer was detected at advanced stage, and its prognosis is poor. Therefore, it is rather important to improve the early diagnosis of pancreatic cancer. In recent years, proteomics is developing rapidly. Proteomics technologies have been widely used in clinical research. Using proteomics technology screening pancreatic cancer tumor markers becomes the research focus,thus we try to find a kind of or a group of pancreatic tumor markers, so as to improve the diagnosis of pancreatic cancer.
出处
《国际外科学杂志》
2012年第6期407-411,共5页
International Journal of Surgery
基金
国家自然科学基金资助项目（No.81071985）
安徽省国际科技合作计划项目（No.1008010038）
安徽省科技攻关计划资助项目（No.07010302203）
安徽省科技攻关计划资助项目（No.11010402172）
