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美罗华联合CHOP方案治疗非霍奇金淋巴瘤的临床观察 被引量:5

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摘要 目的:比较美罗华联合CHOP化疗和单用CHOP方案治疗CD20+的B细胞非霍奇金淋巴瘤的临床疗效及不良反应。方法:17名CD20+的B细胞非霍奇金淋巴瘤患者被分成两组:实验组8例给予CHOP及Rituximab方案治疗,对照组9例单用CHOP方案化疗。3~6疗程后比较2组的疗效及不良反应。结果:美罗华联合CHOP化疗完全缓解(CR)率75.0%(6/8),总有效率(0R)87.5%(7/8);CHOP组CR率55.6%(5/9),0R率66.7%(6/9),2组疗效差异有统计学意义(P<0.05)。美罗华组2年的总生存率为71.6%,CHOP组为39.2%,美罗华联合CHOP化疗组优于CHOP组(P<0.05)。结论:美罗华联合CHOP化疗治疗CD20+的B细胞非何杰金氏淋巴瘤可取得较好疗效,不良反应能耐受。
出处 《新疆医学》 2012年第5期46-48,共3页 Xinjiang Medical Journal
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参考文献5

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