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腹腔内高压患者血清TNF-α、IL-6和IL-8的变化 被引量：4

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摘要 目的:探讨腹腔内高压患者血清肿瘤坏死因子(TNF)-α、白细胞介素6(IL-6)和白细胞介素8(IL-8)的浓度变化。方法:选择综合ICU中腹腔内高压(IAH)患者48例,确诊为IAH后,分别于第1、3、5天采集血标本,用ELISA法测定血清TNF-α、IL-6及IL-8的浓度。结果:在相应的观察时间内,腹内压越高,血清内TNF-α、IL-6、IL-8浓度越高,腹腔内高压持续时间越长,各项观测指标值亦越高(P<0.05)。结论:TNF-α、IL-6、IL-8等炎症因子在腹腔内高压的病理生理机制中起着重要作用。
作者 尹江涛 万兵 孙志伟
机构地区 江苏大学附属医院ICU
出处 《江苏大学学报（医学版）》 CAS 2012年第3期272-274,共3页 Journal of Jiangsu University：Medicine Edition
基金 镇江市科技支撑计划(社会发展)资助项目(FZ2011047)
关键词 腹腔内高压 肿瘤坏死因子-Α 白细胞介素-6 白细胞介素-8
分类号 R619 [医药卫生—外科学]
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参考文献10

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同被引文献26

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江苏大学学报（医学版）
2012年 第3期

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