摘要
目的:研究血小板参数在活动期强直性脊柱炎发病中的作用,探讨其可能的机制及临床价值。方法:采用全血细胞分析仪及免疫学检测方法,检测53名活动期强直性脊柱炎患者和39名健康对照者静脉血中血小板参数及C反应蛋白,进行统计学分析。结果:活动期强直性脊柱炎患者中静脉血中血小板计数与C反应蛋白水平均显著高于健康对照组,血小板平均体积明显低于健康对照组(P<0.05),且血小板计数与C反应蛋白水平存在正相关(r=0.421,P<0.05),血小板平均体积与C反应蛋白存在负相关(r=-0.325,P<0.05)。结论:血小板参数变化与活动期强直性脊柱炎病情活动有关,可以作为监控病情的反应指标,与C反应蛋白有同等的重要作用。
Objective：To explore the role of Platelet parameters（PLT、MPV） in activity ankylosing spondylitis,Discusses the mechanism and clinical value.Methods：by the whole blood cells analyser and immunology detection methods,detected the Venous blood platelets parameter（PLT、MPV）and CRP of 53 cases activity ankylosing spondylitis and 39 cases Health group,And do statistical analysis.Results：the CRP and PLT of activity ankylosing spondylitis are Significantly higher than health group,MPV significantly smaller than healthy group（P =0.000,P0.05）,there is positively correlated between PLT and CRP（r=0.421,P0.05）,MPV and CRP（r=-0.325,P0.05）,negative correlation exists.Conclusion：Platelet parameters（PLT,MPV）have relations with the activity ankylosing spondylitis disease,Can be used as a reaction index condition monitoring.And as the same important role of CRP.
出处
《中医正骨》
2012年第5期13-14,共2页
The Journal of Traditional Chinese Orthopedics and Traumatology
基金
温州卫生局科研项目(2008002)
