摘要
[目的]观察翠云草水提液(SUAE)的祛痰止咳作用。[方法]采用酚红排泌量法、氨水及枸橼酸引咳法,研究SUAE的祛痰、止咳作用。[结果]SUAE中、高剂量组可显著增加小鼠气管酚红排泌量,明显减少浓氨水引起的咳嗽次数,明显延长豚鼠咳嗽的潜伏期,减少枸橼酸刺激后5 min内豚鼠的咳嗽次数。[结论]SUAE具有较强的祛痰、止咳作用。
[Objective] To investigate anti-tussive and expectorant activities of aqueous extract from Selaginella uncinata （SUAE）. [Method] Anti-tussive activity was evaluated using two different models including ammonia-induced mice coughing and citric acid induced guinea pigs coughing. Expectorant activity was evaluated by volume of phenol red in mice＇s tracheas. [Results] SUAE could significantly inhibit mice＇s frequency of cough induced by ammonia, increase guinea pigs＇ latent period of cough and inhibit frequency of cough. [Conclusions] SUAE exhibited anti-tussive, anti-asthmatic and expectorant activities in vivo.
出处
《浙江中医药大学学报》
CAS
2012年第5期563-565,共3页
Journal of Zhejiang Chinese Medical University
基金
浙江省中医药管理局项目(2007CA002)~~
关键词
SOAE
祛痰
止咳
Selaginella uncinata
anti-tussive
expectorant
