摘要
目的 :探讨胆囊切除术预防性应用抗生素的价值。方法 :回顾性研究上海儿童医院、华山医院、儿科医院 1997.1- 1999.10住院病人胆囊切除术共 45 8例 ,分析伤口感染的相关因素并观察不同方案应用预防性抗生素的术后伤口感染情况。结果 :年龄大于 6 5岁、急诊胆囊切除术均为术后伤口感染的危险因素。急诊胆囊切除术胆汁细菌培养阳性率明显升高。术中单一剂量组与术后连续 3天用药组术后伤口感染率无显著差异。结论 :胆道手术应进行预防性应用抗生素 。
Objective:To evaluate the value of antibiotic prophylaxis in cholecystectomy.Methods:In three hospitals 458 patients undergoing cholecystectomy between 1997.1 and 1999.10 were entered into a retrospective audit. Incidence of postoperative wound infection, and of bile cultures growing pathogenic organism were detected in three different prophylactic dose groups.Results:Age greater than 65 years, acute cholecystitis were proved to be risk factors for postoperative wound infections. There was no difference in wound infection rates between a single injection of antibiotic given half an hour before incision and multiple-dose regimens.Conclusion:An adequate prophylactic effect can be expected by a single injection of antibiotic during cholecystectomy, but the routine antibiotic prophylaxis as recommended for biliary surgery in risk groups ,combining with acute cholecystitis, age over 65 years, obstructive jaundice, is still questionable. [FK(WB00001。5]
出处
《肝胆胰外科杂志》
CAS
2000年第1期26-27,共2页
Journal of Hepatopancreatobiliary Surgery
关键词
预防性抗生素
伤口感染
胆囊切除术
antibiotic prophylaxis
wound infection
cholecystectomy
