摘要
目的:研究复合麻醉异丙酚、咪达唑仑、芬太尼用于无痛人工流产中的临床应用。方法:选择ASAⅠ～Ⅱ级人工流产手术患者200例,随机分为观察组与对照组,各100例。观察组给予咪达唑仑总量1mg,芬太尼总量30μg,异丙酚1～1.5mg/kg。对照组依次予以芬太尼总量30μg,异丙酚1～1.5mg/kg。等待孕妇意识完全消失开始手术,若出现四肢扭动,两组均静脉缓慢推注异丙酚20～40mg维持至手术完毕。并记录MAP、HR、SpO2变化、镇痛镇静效果观察及诱导、苏醒时间、异丙酚用量。结果:两组麻醉诱导时间、苏醒及自动离院时间、MAP、HR、SpO2、镇痛镇静效果、人工流产综合征、出血量、宫颈松弛度比较差异均无统计学差异(P>0.05),而异丙酚用量观察组明显少于对照组,差异有统计学意义(P<0.05)。结论:复合麻醉咪达唑仑、异丙酚、芬太尼联合用于无痛人工流产不仅可以减少麻醉药异丙酚的药量,而且镇痛镇静效果好,人工流产手术成功高,安全可靠,值得推广。
Objective ： To explore the effects of propofol with a little dosage of midazolam and fentanyl for colonoseopy anaesthesia.Methods ：ASA Ⅰ-Ⅱ class, two hundred patients were randomly divided into two groups （an observing group and a controlling group）, every group had 100 patients.The observing group was administrated midazolam total 1 mg, fentanyl total 30 μg, propofol 1-1.5 mg/kg.The controlling group was administrated fentanyl total 30 μg, propofol 1-1.5 mg/kg.When the patients＇ eyelash reflex was gone, colonscopy was beginning.If the body still move , use propofol 20-40 mg every time. Observing the changes of blood pressure （BP）, heart rate （HR）, pulse oxygen saturation（SpO2）, and induction time, recovery time, the dosage of propofol. Results ：Induction time, recovery time, the time of leaving hospital and respiration depression have no marked differences （P〉0.05）.The dosage of propofol inthe observing group was less than in the controlling group （P〈0.05）.Conclusion ：Propofol with a little dosage of midazolam and fentanyl for anesthesia in painless, the induced abortion may reduce the dosage of propofol, and it is efficacious and safe.It＇s worth to extend.
出处
《中外医学研究》
2012年第16期6-8,共3页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
复合麻醉
无痛人工流产
异丙酚
咪达唑仑
芬太尼
Composite anest＇esia
Painless in the induced abortion
Propofol
Midazolam
Fentanyl
