摘要
许多因素可以引发或加重支气管哮喘(哮喘),流行病学和临床研究均证实胃食管反流病(GERD)与哮喘的关系密切,特别是一些难以控制、病情严重及频繁发作的哮喘多与GERD有关。GERD和哮喘相互影响、互为因果,致使哮喘的症状长时间得不到良好的控制。因此非常有必要更好地认识和研究GERD及其与哮喘的关系,也是近年来成为全球性医学研究的热点课题之一,现将其发病机制、病理生理、临床表现、诊断和治疗的研究进展概述如下。
Many factors can cause or aggravate asthma. Epidemiological and clinical studies have confirmed that gastro esophageal reflux disease （GERD） and bronchial asthma are closely related. Particularly, it is difficult to control, because a serious condition of more frequent asthma attacks is linked with GERD. Thus GERD and asthma influence mutually on each other, so in the result, the symptoms of asthma are not well controlled for a long time. Therefore it is necessary to understand and study well the GERD and its relationship with asthma. In recent years, it became a global hot topic in the field of medical research. Now its pathogenesis, pathophysiology, clinical manifestations, diagnosis and progress in treatment are outlined below.
出处
《实用儿科临床杂志》
CAS
CSCD
北大核心
2012年第9期712-715,共4页
Journal of Applied Clinical Pediatrics
关键词
支气管哮喘
胃食管反流
发病机制
bronchial asthma
gastro esophageal reflux
pathogenesis
