摘要
环糊精是一类由6～8个D-型葡萄糖连接而成的环聚多糖分子,目前已广泛应用于化学和生物学的许多领域.综述了一些生物活性的环糊精超分子组装体,如环糊精假聚轮烷、环糊精/金纳米粒子组装体、环糊精/富勒烯组装体、环糊精/碳纳米管组装体等的构筑及其与核酸的相互作用,如对核酸的切割、凝聚、传递作用和对核酸酶的抑制作用等方面的研究进展.
Cyclodextrins （CDs） are a class of cyclic oligosaccharides with six to eight D-glucose units and widely applied in many fields of chemistry and biology. This review deals with the representative contributions in the construction of some bio- active cyclodextrin-based supramolecular assemblies, including cyclodextrin polypseudorotaxane, cyclodextrin/gold nanopar- ticle assembly, cyclodextrin/fullerene assembly, cyclodextrirdcarbon nanotube assembly, and their interactions with nucleic acids, including the nucleic acid cleavage, condensation, delivery and the inhibition of nucleic acid enzymes.
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
2012年第5期805-814,共10页
Chinese Journal of Organic Chemistry
基金
973重大研究计划(No.2011CB932500)
国家自然科学基金(Nos.20932004
91027007)资助项目~~
关键词
环糊精
核酸
超分子组装体
cyclodextrin
nucleic acid
supramolecular assembly
