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肌酸对新生大鼠缺氧心肌葡萄糖摄取的影响 被引量:1

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摘要 目的:研究肌酸对新生大鼠缺氧心肌葡萄糖摄取的影响,探索改善和调控缺氧心肌能量代谢的因素。方法:将原代培养的新生大鼠心肌细胞随机分为对照组、缺氧组、缺氧联合肌酸组,测定各组心肌细胞2-〔3H〕-脱氧葡萄糖(2-〔3H〕DG)平均摄取率。结果:肌酸浓度为0.5 mmol/L时,心肌细胞对2-〔3H〕DG的摄取率最高。同对照组相比,缺氧组、缺氧联合肌酸组2-〔3H〕DG平均摄取率明显增加。其中缺氧联合肌酸组葡萄糖平均摄取率增加最为明显(P<0.05)。结论:肌酸能够增加缺氧心肌细胞葡萄糖平均摄取率。
出处 《中国妇幼保健》 CAS 北大核心 2012年第15期2346-2347,共2页 Maternal and Child Health Care of China
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