摘要
目的探讨应变率成像(SRI)技术评价慢性肺源性心脏病(简称肺心病)患者左心功能的价值。方法选取慢性肺心病患者64例(心功能代偿组30例,心功能失代偿组34例)及正常对照组30例,应用SRI技术测量并计算左心室平均心肌收缩期峰值应变率(mSRs)、舒张早期峰值应变率(mSRe)和舒张晚期峰值应变率(mSRa),并与常规超声心动图的左心功能不全检出率进行比较。结果与正常对照组比较,心功能代偿组的mSRs以及心功能失代偿组的左心室射血分数(LVEF)、左心室短轴缩短率(LVFS)和mSRs均显著降低(P值均<0.05)。与心功能代偿组比较,心功能失代偿组的LVEF、LVFS和mSRs均显著降低(P值均<0.05)。与正常对照组比较,心功能代偿组和心功能失代偿组的舒张早期最大血流速度(E)、E/舒张晚期最大血流速度(A)、mSRe、mSRe/mSRa均显著降低(P值均<0.05),A、mSRa均显著升高(P值均<0.05)。与心功能代偿组比较,心功能失代偿组的E、E/A、mSRe、mSRe/mSRa均显著降低(P值均<0.05),A、mSRa均显著升高(P值均<0.05)。SRI对心功能代偿组和心功能失代偿组左心收缩功能不全及舒张功能不全的检出率均高于常规超声心动图,其中SRI对心功能代偿组左心收缩功能不全的检出率显著高于常规超声心动图(P<0.05)。结论 SRI技术较常规超声心动图能更敏感、快速地定量评价慢性肺心病患者的左心功能,并能估测早期左心室收缩功能的变化。
Objective To explore the role of strain rate imaging （SRI） in evaluation of left ventricular function in the patients with chronic pulmonary heart disease. Methods Totally 64 patients with chronic pulmonary heart disease （30 in cardiac compensation group and 34 in cardiac decompensation group） and 30 normal control were enrolled in this study. The mean left ventricular myocardial peak systolic strain rate （mSRs）, peak early diastolic strain rate （mSRe） and peak late diastolic strain rate （mSRa） were measured by SRI technology. The detection rates of left ventricular dysfunction by SRI and conventional echocardiography were compared. Results Compared with normal control, mSRs in cardiac compensation group, left ventricular ejection fraction （LVEF）, left ventricular fractional shortening （LVFS） and mSRs in cardiac decompensation group were significantly decreased （P〈0.05）. LVEF, LVFS and mSRs in cardiac decompensation group were significantly lower than those in cardiac compensation group （P〈0.05）. Compared with normal control, late diastolic peak velocity （A） and mSRa were significantly increased, and early diastolic peak velocity （E）, ElA, mSRe and mSRelmSRa were significantly decreased in both cardiac compensation group and cardiac decompensation group （P〈0.05）. Compared with cardiac compensation group, E, ElA, mSRe and mSRelmSRa were significantly decreased, and A and mSRa were significantly increased in cardiac decompensation group （P〈 0.05）. The detection rates of left ventricular systolic and diastolic dysfunction by SRI were higher than conventionalechocardiography. Especially, the detection rate of left ventricular systolic dysfunction in cardiac compensation group by SRI was significantly higher than conventional echocardiography （P〈0.05）. Conclusion SRI is more sensitive and rapid than conventional echocardiography in quantitative assessment of left heart function in patients with chronic pulmonary heart disease. Moreover, SRI can estimate
出处
《上海医学》
CAS
CSCD
北大核心
2012年第3期231-234,166,共4页
Shanghai Medical Journal
关键词
超声心动描记术
应变率
左心功能
慢性肺源性心脏病
Echocardiography
Strain rate
Left heart function
Chronic pulmonary heart disease
