摘要
细胞治疗与基因治疗的相互交融形成了更行之有效的干细胞/基因联合治疗,本文简要介绍干细胞/基因联合治疗中常用的细胞类型、各种载体以及它们的优缺点;例举了迄今已报道有成效的某些人类疾病的治疗或动物实验治疗的结果。此外,指出干细胞/基因联合治疗中可能遇到的致瘤性问题及其对策。
The merge of cell therapy with gene therapy forms a more effective combined stem cell therapy/gene therapy. An introduction to combined stem cell therapy/gene therapy is made in this minireview briefly, including the often used cell types, vectors and their advantages and disadvantages. Examples of some diseases in human being or in animals which have been treated with combined stem cell therapy/gene therapy successfully are given also. It is pointed out that carcinogenesis might occur during the treatment and how to overcome such problems.
出处
《解剖学报》
CAS
CSCD
北大核心
2012年第3期289-292,共4页
Acta Anatomica Sinica
关键词
细胞治疗
间充质干细胞
造血干细胞
基因治疗
致瘤性
Cell therapy
Mesenchymal stem cell
Hemotopoietic stem cell
Gene therapy
Carcinogenesis
