摘要
microRNA(miRNA)功能异常在肿瘤发生发展中具有极其重要的作用。笔者就miRNA的合成与功能,以及miRNA功能异常在肿瘤细胞的周期、凋亡和浸润转移等恶性表型中的作用进行综述,以探讨其在肿瘤早期诊断与复发监测中的意义。
MicroRNA（miRNA） dysfunction contributes critically to the occurrence and development of cancer.This paper reviews the synthesis and biological function of miRNA,as well as the contributions of miRNA dysfunction to the malignant phenotypes of tumor cells involving the cell cycle,apoptosis,invasion,and metastasis,so as to help understand its significances in the early detection and recurrence surveillance of cancer.
出处
《中国普通外科杂志》
CAS
CSCD
北大核心
2012年第5期602-606,共5页
China Journal of General Surgery
