摘要
以α-D-甲基吡喃葡萄糖苷为原料,合成了2,3,4,6-四-O-异丁酰基-α-D-甲基吡喃葡萄糖苷(Ⅰ)、2,3,4,6-四-O-异戊酰基-α-D-甲基吡喃葡萄糖苷(Ⅱ)、2,3,4,6-四-O-3′-甲基戊酰基-α-D-甲基吡喃葡萄糖苷(Ⅲ),并根据1H NMR和HRMS进行了糖酯结构确证。结果表明:①合成产物为目标产物;②葡萄糖苷与酰氯的物质的量比为1∶4.4或1∶4.6,反应温度60℃,反应时间2 h,目标糖酯的合成产率最高。
Methyl 2, 3, 4, 6-tetra-O-isobutyryl-a-D-glucopyranoside, methyl 2, 3, 4, 6-tetra-O-isovaleryl-a-D- glucopyranoside, and methyl 2, 3, 4, 6-tetra-O-（3-methylvaleryl）-a-D-glucopyranoside were synthesized from methyl a-D-glucopyranoside. The molecular structures of the tetraesters were verified by^1H NMR and HRMS. The results indicated： 1） The synthetic compounds were target products. 2） The highest yield of the target glucose tetraesters was obtained when molar ratio of methyl a-D-glucopyranoside to acyl chloride was 1：4 or 1：4.6 and reacted at 60 ℃ for 2 hours,
出处
《烟草科技》
EI
CAS
北大核心
2012年第5期27-30,共4页
Tobacco Science & Technology
基金
国家烟草专卖局资助项目"卷烟烟气味觉特征及调控研究"(110200901002)
关键词
糖酯
异丁酸
异戊酸
3-甲基戊酸
卷烟
Glucose ester
Isobutyric acid
Isovaleric acid
3-Methyl pentanoi
acid
Cigarette
