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肝动脉化疗栓塞及注射^(32)P-胶体、无水乙醇综合序贯介入治疗原发性肝癌疗效分析 被引量:3

Therapeutic effect of combination and sequencial interventional treatment on primary liver cancer with transcatheter arterial chemoembolization combined with radioactive colloidal phosephate and percutaneous ethanol injection under ultrasound
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摘要 目的 评价肝动脉化疗栓塞(TACE) 及B 超引导下注射32P胶体、无水乙醇(PEI) 综合序贯介入治疗原发性肝癌的临床价值。方法 51 例中晚期肝癌分为2 组,23 例综合序贯应用TACE+ 32P+ PEI治疗,28 例单纯应用TACE 治疗。结果 综合序贯组肿瘤缩小率、肿瘤完全坏死率、AFP下降率分别为91 .29 % 、80 .00 % 、87 .5 % ,而单纯TACE组分别为39.27% 、30 .43% 、41 .46 % ,两组比较有显著性差异( P<0 .01),6 个月、1、2 、3 年生存率综合序贯组分别为95.65 % 、86.95% 、56 .52 % 、20.73 % ,而单纯TACE 组分别为64.28% 、39.28 % 、17 .85 % 、00 .00 % (P< 0.01) 。结论 TACE+ 32P+ PEI的综合序贯介入治疗是提高中晚期原发性肝癌患者生存率的有效方法。 Objective To evaluate the clinical efficacy of transcatheter arterial chemoembolization (TACE) combined with radioactive colloidel phosephate ( 32 P) and percutaneous ethanol injection (PEI) in the treatment of primary liver cancer (PLC). Methods 51 cases of moderate and advanced stages of PLC were divided into two groups, 23 cases were treated with TACE and followed subsequently by 32 P and PEI (group A). 28 cases were treated with TACE alone (group B). Results The rates of reduction in tumor diameter and tumor complete necrosis and the decline in serum AFP level in group A were 91.29%, 80.00% and 87.5%, while those of group B were 39.27%, 30.43% and 41.46% respectively. There was significant difference between the two groups ( P <0.01). The 6 month, 1-,2-,3-year survival rates of group A were 95.65%, 86.95%, 56.52%, 20.73%, respectively; in contrast, those of group B were 64.28%, 39.28%, 17.85%, 00.00%,respectively ( P <0.01). Conclusions The combination and sequencial interventional treatment on PLC with TACE combined with 32 P and PEI is an efficient method for increasing the survival rate.
出处 《介入放射学杂志》 CSCD 2000年第1期22-24,共3页 Journal of Interventional Radiology
关键词 肝细胞癌 治疗性栓塞 无水乙醇 胶体磷 Carcinoma hepatocellular Emboization therapoeutic Ethanol Colloid phosephate Ultrasonc intravention
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