摘要
目的:评价加巴喷丁治疗带状疱疹急性期神经痛的疗效与安全性。方法:60例患者随机分为试验组与对照组(每组30例),两组均用膦甲酸钠、维生素B1、甲钴胺等治疗,试验组加用加巴喷丁,对照组加用卡马西平治疗。采用视觉模拟评分法评价患者治疗前后疼痛程度及治疗效果,同时观察患者的不良反应。结果:治疗组视觉模拟评分法评分明显低于对照组(P<0.05),疗效优于对照组。结论:加巴喷丁治疗带状疱疹急性期神经痛具有较好的疗效,副作用小。
Objective: To observe the efficacy and safety of gabapentin in the treatment of acute herpes zoster neuralgia.Methods: All patients were treated with Foscarnet Sodium,vitamin B1 and methylcobalamin.On this basis,sixty patients were randomly divided into two groups,which were treated with either gabapentin(treatment group) or carbamazepine(control group).An evaluation of pain was done by using visual analogue scales(VAS) before and after treatment and adverse reactions of gabapentin and carbamazepine were observed.Results: The VAS scores of the treatment groups were significantly lower,and the total effective rate of treatment group was higher than that of control group.Conclusion: Gabapentin is effective in the treatment of acute herpes zoster neuralgia and with mild side effects.
出处
《川北医学院学报》
CAS
2012年第2期162-164,共3页
Journal of North Sichuan Medical College
关键词
带状疱疹
加巴喷丁
神经痛
视觉模拟评分法
疗效
Herpes zoster
Gabapentin
Neuralgia
Visual analogue scales
Curative effect