摘要
目的:了解欠发达地区HIV母婴传播干预措施利用状况及其影响因素,为更好制订预防HIV母婴传播措施提供依据。方法:采用回顾性队列研究的方法,采用自行设计的问卷进行面对面问卷调查,收集社会人口学特征、HIV确认时间,抗逆转录病毒药物应用情况及开始应用时间等。结果:1 045例HIV感染的孕产妇27.3%(285/1 045)是在妊娠前获知HIV感染;89.4%(934/1 045)选择分娩,抗病毒药物的应用率为84.5%(789/934)。多因素分析结果显示高中或以上文化程度的HIV感染孕产妇抗病毒药物应用率(80.5%)高于初中或以下文化程度的孕产妇(86.8%),其OR值为1.587。月收入800～1 000元的HIV感染的孕产妇抗病毒药物应用率高于家庭月收入≤800元,其OR值为0.024。妊娠前获知HIV感染的孕产妇抗病毒药物应用率高于妊娠后获知HIV感染的孕产妇,其OR值为1.602。结论:文化程度高、家庭经济状况好、妊娠前获知HIV感染状况有利于HIV感染孕产妇尽早接受抗病毒药物等HIV母婴传播干预措施的利用。
Objective：To understand the utilization and influencing factors of interventional measures of human immunodeficiency virus（HIV） mother-to-child transmission in underdeveloped areas,provide a basis for making measures to prevent HIV mother-to-child transmission. Methods：A retrospective cohort study was conducted,a self-designed questionnaire was used for face-to-face investigation;socio-demographic characteristics,confirmation time of HIV,the application of antiretroviral drugs,and the start time were collected. Results：Among 1 045 pregnant women with HIV infection,285 women（27.3%） were found with HIV infection before pregnancy;934 women（89.4%） chose delivery,the application rate of antiviral drugs was 84.5%（789/934）.The results of multivariate regression analysis showed that the application rate of antiviral drugs among HIV-infected pregnant women with senior high school educational level or above was 80.5%,which was significantly higher than that among HIV-infected pregnant women with junior high school educational level or above（86.8%）,OR=1.587.The application rate of antiviral drugs among HIV-infected pregnant women whose family monthly income was from 800 to 1 000 was higher than that among HIV-infected pregnant women whose family monthly income was less than 800（including 800）,OR=0.024.The application rate of antiviral drugs among HIV-infected pregnant women who were found with HIV before pregnancy was higher than that among HIV-infected pregnant women who were found with HIV after pregnancy,OR=1.602. Conclusion：High educational level,good family financial situation,and confirming HIV infection before pregnancy are helpful to early application of interventional measures of HIV mother-to-child transmission,such as antiviral drugs.
出处
《中国妇幼保健》
CAS
北大核心
2012年第12期1773-1777,共5页
Maternal and Child Health Care of China
关键词
HIV
妊娠
孕产妇
母婴传播
Human immunodeficiency virus
Pregnancy
Pregnant women
Mother-to-child transmission
