摘要
目的探讨糖化血红蛋白在2型糖尿病患者中与血糖血脂的相关性,进一步观察糖化血红蛋白检测的临床意义。方法 1 126例2型糖尿病患者均为我院进行治疗的病例;选取同期来我院进行体检的健康研究对象950例,检测两组患者的血糖、血脂生化指标及其糖化血红蛋白。结果与对照组的各项观察指标比较,研究组的FPG、TC、TG、LDL-C、ApoB及其HbA1c均明显较高(P<0.05),而HDL-C、ApoA1均明显较低(P<0.05)。HbA1c与HDL-C(r=-0.530,P<0.05)及ApoA1(r=-0.218,P<0.05)呈明显的负相关,而与其他观察指标均呈明显的正相关;FPG与HDL-C(r=-0.009,P>0.05)及ApoA1(r=-0.102,P>0.05)之间无明显的相关性,而与其他的观察指标均呈明显的正相关(P<0.05)。结论对2型糖尿病患者进行糖化血红蛋白检测具有重要的临床意义,其检测数值与血糖、血脂均具有明显的相关性。
Objective To investigate the glycosylated hemoglobin in type 2 diabetic patients with blood glucose and lipids in the correlation, further observation glycated hemoglobin clinical significance. Methods All 1 126 cases of type 2 diabetics were selected from our hospital; 950 cases of health were selected in our hospital, blood glucose, the blood biochemical in- dicators and glycosylated hemoglobin between two groups were tested. Results A total of Compared with control group, FPG, TC, TG, LDL-C, ApoB and HbAlc of the study group were significantly higher （P 〈 0.05 ）, while HDL-C, ApoAl were significantly lower （P 〈 0.05）, HbAlc and HDL-C （r = -0.530, P 〈 0.05）, ApoA1 （r =- 0.218, P 〈0.05） showed sig- nificant negative correlation relationships, with other observation indicators had a significant positive correlation; FPG and HDL-C （r = -0.009, P 〉 0.05）, ApoA1 （r = -0.102, P 〉 0.05） with no significant correlation, with other observation indi- cators had a significant positive correlation （P 〈 0.05）. Conclusion Glycosylated hemoglobin test in type 2 diabetic patients has important clinical significance, the test values and blood glucose and blood lipids have obvious relevance.
出处
《中国现代医生》
2012年第12期40-41,72,共3页
China Modern Doctor
关键词
2型糖尿病
糖化血红蛋白
血糖
血脂
Type 2 diabetes
Glycosylated hemoglobin
Glucose
Lipids
