摘要
目的 :探讨非洛地平对原发性高血压患者血脂、血糖及血尿酸的影响。方法 :对 42例原发性高血压病患者给予非洛地平治疗 ,10mg/次 ,口服 ,1次 /d(或 2次 /d) ,共 6个月 ,观察治疗前后患者血糖、血脂及血尿酸的变化。结果 :治疗前收缩压为 (2 5 0 0± 6 0 0 )kPa ,舒张压为 (13 90± 2 40 )kPa ,胆固醇 (TC)为 (6 70± 2 30 )mmol/L ,高密度脂蛋白胆固醇 (HDL ch)为 (1 12± 0 2 5 )mmol/L ;治疗后收缩压为 (18 90± 2 10 )kPa ,舒张压为 (12 10± 1 90 )kPa ,TC为 (4 90± 1 5 0 )mmol/L ,HDL ch为 (1 42± 0 5 0 )mmol/L。二者相比差异均有显著性 (P <0 .0 5 ) ,其余指标治疗前后相比差异无显著性 (P >0 .0 5 )。结论 :非洛地平适用于原发性高血压病以及合并有糖尿病和血脂代谢异常的高血压患者使用 。
Aim:To investigate the effect of felodipine on blood lipid,sugar and uricacid in patients with essential hypertension.Methods:42 patients with essential hypertension were given felodipine,10 mg per day or 10 mg BID,po,and the total time of treatment was 6 weeks.Before and after treatment,the blood was collected from patients to determine the alternation of blood sugar,lipid and uricacid.Results:There was a significant difference( P <0.05) between systolic blood pressure(SBP,(25.00±6.00) kPa),diastolic blood pressure(DBP,(13.90±2.40) kPa),total cholesterol(TC,(6.7±2.3) mmol/L) and high density lipoprotein cholesterol(HDL ch,(1.12±0.25) mmol/L) in patients before treatment,and SBP(18.9±2.1) kPa,DBP(12.1± 1.9) kPa, TC(4.9±1.5) mmol/L after treatment( P >0.05).Conclusion:Felodipine is suitable for treating patients with essential hypertension and hypertension complicated with diabetes and blood lipid disorder,and the efficacy of felodipine on blood pressure smooth and dependable.
出处
《河南医科大学学报》
CAS
2000年第1期85-86,共2页
Journal of Henan Medical University
