摘要
维生素C(vitamin C,VC)是人体的必需营养元素,在保护人类健康和动物生长过程中起到不可代替的重要作用。由于VC自身易被氧化降解,开发稳定的高附加值VC衍生物就成为人们研究的热点。目前,VC衍生物主要有VC盐、VC酯和VC糖苷3种形式,其中VC糖苷类衍生物稳定性高,生理活性与VC最接近,近年来备受国内外学者的关注。因此,本文就VC上的C2-,C5-及C6-糖苷类衍生物的国内外研究进展进行了归纳总结。
Vitamin C is listed in the essential nutrition elements of human beings or animals,and plays an important role in protecting human health and animal growth.The well-known susceptibility of vitamin C to oxidative degradation has led to great interest in its derivatives with increased stability in recent years.The vitamin C derivatives can be classified as salt,ester and saccharide derivatives.Ascorbyl glucoside derivates represent a kind of important vitamin C derivatives.Many domestic and overseas research papers have reported various saccharide derivatives of vitamin C.Therefore,in this review we summarized the latest research progress of ascorbyl glucoside derivates with chemical modification of hydroxyl group at the C2-,C5-and C6-position of vitamin C.
出处
《中国新药杂志》
CAS
CSCD
北大核心
2012年第7期761-766,共6页
Chinese Journal of New Drugs
基金
国家科技支撑计划子课题(2009BAI72B03)
关键词
维生素C
VC衍生物
VC糖苷类衍生物
vitamin C
derivatives of vitamin C
ascorbyl glucoside derivates
