摘要
目的 :探讨手术为主综合治疗鼻咽癌 ,提高患者的生存质量。方法 :选取无颅底骨侵犯和远端转移的鼻咽癌 14例 (其中 3例是放疗不能控制者 ) ,按鼻咽癌临床分期标准 ,Ⅰ期 6例 ,Ⅱ期 3例 ,Ⅲ期 5例 ,行手术为主、术中冷冻、术后放疗和 (或 )化疗为辅的综合治疗。 14例中 10例采用经腭进路手术 ,其中 7例采用软硬腭舌形切口 ,舌形的尖端指向悬雍垂 ,3例采用软硬腭垂直裂开切口 ;4例采用鼻侧切开入路手术。结果 :14例分别观察 1～ 5年 ,未见鼻咽癌复发。其 5年、3年和 1年生存率分别为 5 0 0 0 % (7/ 14)、5 7 14% (8/ 14)和 92 86 % (13/ 14)。其中1例术后因肺转移癌死亡。结论 :手术为主综合治疗鼻咽癌是可行的、有效的。因无鼻咽癌复发 ,无须重复放疗 ,可防止重复放疗的并发症 ,提高患者的生存质量。
Objective: To improve the living quality of patients with nasopharyngeal cancer (NPC) by surgery as the predominant therapy Methods: Fourteen patients with NPC without involvement of skull base or metastasis were treated by surgery as the predominant therapy of comprehensive treatment (three of them were not radiosensitive) According to the criteria of clinical stage of NPC: Stage Ⅰwas 6 cases, Stage Ⅱ3 cases and Stage Ⅲ5 cases The comprehensive treatment consisted of frozen therapy, postoperative radiation, chemotherapy and operation as the predominant management In the overall patients, 10 cases underwent transpalatal operation (a tongue-form incision of the soft-hard palate with the tip of the incision toward uvula was performed on 7 cases, and a vertical split incision of soft-hard palate was made on 3 cases) and lateral rhinotomy approach was performed on other 4 cases Results: After 1 to 5 year follow-up, no recurrence was observed The 1-, 3-and 5-year survival rates of these patients were 92 86%(13/14), 57 14%(8/14) and 50 00%(7/14) respectively One of them died of postoperative lung metastasis Conclusion: Surgery as the predominant therapy of comprehensive treatment of NPC is feasible and effective There is no recurrence or repeated radiotherapy and its complications so that the patient will have a better living quality
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
2000年第5期343-345,共3页
Chinese Journal of Clinical Oncology
关键词
鼻咽癌
外科手术
综合治疗
生存质量
Nasopharyngeal carcinoma\ Surgery\ Comprehensive treatment
