摘要
目的探讨足月低体重儿围产期的影响因素。方法对52例足月低体重儿临床资料进行回顾性分析。结果双胎妊娠、妊高症、妊娠期胆汁淤积症、先天性遗传代谢病是引起足月低体重儿的主要因素。足月低体重儿与正常体重足月儿相比,并发症及死亡率均明显升高。从本资料的统计可以看出,足月低体重儿21-三体综合症和先天性畸形发生率较正常体重新生儿明显增高,两者相比差异有统计学意义。结论足月低体重儿病因较复杂,临床并发症多样。加强孕产期保健,对出现异常围产因素的孕母尽早干预,对高龄产妇及有遗传性疾病家族史人群应积极普遍推广孕早期羊水细胞或绒毛膜细胞染色体检测是降低足月低体重儿出生、提高足月低体重儿的生命质量和降低远期发病率的关键。
Objective To assess the perinatal risk factors of low birth weight in fullterm neonates. Methods A retrospec tive study was conducted on 52 cases of fullterm neonates with low birth weight. Results Twin pregnancy, PIH （ PregnancyIn duced Hypertension）, ICP（ Intrahepatic Cholestasis of Pregnancy）, and congenital metabolic disorders were unveiled to be major risk factors resulting in low birth weight among fullterm neonates, with remarkably increased risks of complications and mortality rate, comparing with the normal group. Differences were shown in this study to lie on raised morbidity of Down＇ s syndrome and congenital malformation with statistical significance. Conclusion Low birth weight in fullterm neonates was a consequence of multiple risk factors and a cause of various complications clinically. Good maternal care ,prompt intervention on perinatal risk fac tors, as well as early karyotype study with amniotic or chorionic cells among the population with advanced maternal age and/or rel evant family history, were proven to play crucial roles in decreasing morbidity, improving quality of life, and preventing from fur ther complications of fullterm neonates with low birth weight.
出处
《中华全科医学》
2012年第4期532-532,559,共2页
Chinese Journal of General Practice
关键词
足月低体重儿
病因分析
Low birth weight, Full-term
Etiology analysis
