摘要
研究了一种碱性条件下由邻氨基芳香腈1与醛2一锅合成4(3H)-喹唑啉酮3的新方法.反应经由亲核加成、分子内的Pinner关环、Dimroth重排和氧化脱氢串联转化而成.产物结构经1H NMR,13C NMR,IR和元素分析确证.
A series of 4（3H）-quinazolinones 3 were obtained from the one-pot synthesis of available substituted aromatic o-aminonitriles 1 with aldehydes 2 in the present of base.This tandem transformation was included in addition,intramolecular Pinner reaction,Dimroth rearrangement and oxidative dehydrogenation.The structures of products were characterized by 1H NMR,13C NMR,IR spectra and elemental analysis.
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
2012年第3期532-537,共6页
Chinese Journal of Organic Chemistry
