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富于细胞性神经鞘瘤2例临床病理分析 被引量:15

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摘要 目的探讨富于细胞性神经鞘瘤临床病理学特点及其诊断与鉴别诊断。方法对2例富于细胞性神经鞘瘤进行临床资料分析、组织学形态和免疫表型观察。结果富于细胞性神经鞘瘤好发于腹膜后,临床上表现为缓慢生长的无痛性肿块。大体肿瘤呈圆形、椭圆形,包膜完整,切面实性,灰白、灰黄色。镜下肿瘤具有完整的包膜,在包膜外或包膜下可见淋巴细胞聚集灶,形成袖套样结构。免疫组化肿瘤细胞S-100、GFAP和CD57均弥漫强阳性,不表达CK(AE1/AE3)、desmin、SMA、CD34、CD117和DOG1。结论富于细胞性神经鞘瘤是一种少见的假肉瘤性病变,大体表现、组织学特点是其诊断及鉴别诊断的主要依据,免疫组化标记有助于诊断和鉴别诊断。
作者 高金莉
出处 《临床与实验病理学杂志》 CAS CSCD 北大核心 2012年第3期341-342,共2页 Chinese Journal of Clinical and Experimental Pathology
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参考文献10

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二级参考文献13

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