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一例孟鲁斯特钠诱发的精神异常患者的药学监护体会 被引量:12

Pharmaceutical care on a patient with montelukast sodium-induced psychosis
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摘要 目的对1例支气管哮喘急性发作伴肺部感染的患者进行跟踪治疗,探讨患者在药物治疗中出现精神异常的原因。方法检索国内外关于可疑药物—孟鲁斯特钠等致精神异常的相关文献,整理相应的理论依据,为临床药物治疗提出合理建议。结果诱发精神异常等不良反应的药物较多,分析患者所用药物,锁定可疑药物孟鲁斯特钠和莫西沙星,予及时停用孟鲁司特钠,10 d后患者病情好转出院。结论有精神性疾病的哮喘患者使用孟鲁斯特钠时,需密切关注该药引起的精神异常,减少药害事件的发生。 Objective To explore the reasons for mental disorders in the course of drug treatment,by tracking the treatment of a case of acute exacerbation of bronchial asthma complicated with lung infection.Methods Literatures concerning suspected drug-montelukast sodium-induced psychosis in domestic and international journals were reviewed,the corresponding theory basis was sorted out,then the reasonable suggestions for clinical therapy was put forward.Results Clinical pharmacists identified the suspected drug of montelukast sodium and moxifloxacin by analyzing for therapeutic drugs,and stopped using montelukast sodium in time for the patient.As a result,the patient′s condition improved,and he was discharged after 10 d.Conclusion As montelukast sodium is used for treating asthma patients with mental disorders,close attention should be paid to drug-induced psychosis,to reduce the incidence of drug induced injury.
作者 周宏 张瑞芬
出处 《实用药物与临床》 CAS 2012年第2期95-96,共2页 Practical Pharmacy and Clinical Remedies
关键词 支气管哮喘 抑郁症 孟鲁司特钠 莫西沙星 药学监护 Bronchial asthma Depression Montelukast sodium Moxifloxacin Pharmaceutical care
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