摘要
参考近4年30余篇相关文献,选择以冠心病与2型糖尿病为主要研究内容的文献13篇,按冠心病合并糖尿病的流行病学的现状、冠心病合并糖尿病的病理生理、发病原因与机制、冠心病合并糖尿病的临床特点与诊断、冠心病合并糖尿病的处理原则、糖尿病并冠心病的早期筛查与诊断进展进行分类。结果显示冠心病是目前危害人类生命健康的重大疾病。糖尿病与冠心病的关系密切,冠心病患者合并高血糖比例较高,临床症状多不典型、病死率高、预后差,临床合并症多且控制不理想,低脂联素、高纤溶酶原激活物抑制剂1(PAI-1)、高尿酸(UA)血症、微量白蛋白尿、血浆促心肌素-1(CT-1)、超敏-C反应蛋白(hsCRP)及血脂水平等对早期发现2型糖尿病合并冠心病有一定意义。提示冠心病与2型糖尿病关系密切,应积极关注老年冠心病患者的血糖,并对血糖异常者及早进行干预。
More than thirty related articles published in the authoritative magazines in the latest four years were refered.Thirteen ones on CHD and T2DM were chosen and classed according to the epidemiology of CHD with DM status,the pathophysiology of CHD with DM,the etiology and mechanisms of CHD with DM,the clinical features of CHD with DM,the principles,screening and diagnosis progress of CHD with DM.Results display of CHD is the major risk diseases of human life and health.CHD is closely related to DM.The proporation of patients with CHD and high blood sugar is high;The clinical symptoms are atypical,high mortality,poor prognosis,more clinical complications and difficult to control.So low-adiponectin,high plasminogen activator inhibitor-1(PAI-1),Hyperuricemia Microalbuminuria,microalbuminuria,Cardiotrophin-1(CT-1),hypersensitive C-reactive protein(hsCRP) and serum lipids concentration have a certain significance to detect type T2DM with CHD.Prompt to CHD is closely related to T2DM.More attention should be actively paid to blood sugar of old patients with CHD and early intervention should be given to patients with abnormal blood sugar levels.
出处
《中国当代医药》
2012年第3期12-13,21,共3页
China Modern Medicine
关键词
冠心病
2型糖尿病
研究
干预
Coronary heart disease
Type 2 diabetes mellitus
Research
Intervention