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慢性应激对Ⅱ型糖尿病模型大鼠血清IL-2、IL-4和IL-18表达的影响 被引量:3

Chronic Stress on IL-2、IL-4、IL-18 Content in SD Rats
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摘要 目的:通过测定慢性应激条件下的II型糖尿病模型大鼠血清IL-2、IL-4、IL-18含量,揭示慢性应激对II型糖尿病大鼠免疫功能的影响。方法:对应激组大鼠进行为期4周的强迫寒冷游泳与束缚刺激后,比较健康对照组与健康应激组、模型对照组与模型应激组的差异。结果:健康对照组和健康应激组IL-2测定值差异有统计学意义;模型对照组和模型应激组IL-4、IL-18测定值差异有统计学意义(P<0.01)。结论:2型糖尿病大鼠的免疫功能更易受到慢性应激影响。 Objective: By measuring the granting of chronic stress in rats with type 2 diabetes,serum IL-2、IL-4 and IL-18 content,to explore the chronic stress on immune function in type 2 diabetic rats.Methods: Compare the control group with the chronic stress group,and diabetic model group with the chronic stress+diabetes mellitus model group,after 4 weeks forced cold swimming and fetter on the chronic stress group and the chronic stress+diabetes mellitus model group.Results: Chronic stress can impact type 2 diabetic rats' immune function.
出处 《中国临床心理学杂志》 CSSCI CSCD 北大核心 2012年第1期35-36,共2页 Chinese Journal of Clinical Psychology
基金 山西医科大学大学生创新基金(2009-163)
关键词 慢性应激 免疫功能 IL-2 IL-4 IL-18 Chronic stress Immune function IL-2 IL-4 IL-18
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同被引文献33

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