摘要
许多生物标志物的高表达与垂体腺瘤侵袭性有关,其中增殖细胞核抗原(PCNA)是与细胞增殖有关的一个生物标志物,它的高表达被认为是判断垂体腺瘤侵袭性的重要指标。它的检测对指导垂体腺瘤术后痊愈和治疗有十分重要的意义,而且它与垂体腺瘤的其他侵袭性生物标志物也存在着一定的联系。现就PCNA与侵袭性垂体腺瘤以及其他生物标志物的关系特点予以综述。
High expression of many biomarkers is related with invasiveness of pituitary tumors.Proliferating cell nuclear antigen（PCNA）is a biomarker of cellular proliferation.High expression of PCNA can be an important index to indicate invasiveness of pituitary tumors.So detecting PCNA is considered to have great clinical significance to predict prognosis and direct therapy measure of pituitary tumors,and certain relation exists between its expression and others biomakers of pituitary tumors as well.Here is to review the correlation between PCNA and invasive pituitary tumors and other biomakers.
出处
《医学综述》
2012年第3期371-374,共4页
Medical Recapitulate
关键词
增殖细胞核抗原
生物标志物
侵袭性
垂体腺瘤
Proliferating cell nuclear antigen
Biomarkers
Invasiveness
Pituitary tumors
