摘要
目的研究肝硬化门静脉高压患者胆道运动功能的改变，分析其临床意义。方法采用放射性核素定量肝胆显像技术测定了４０例肝硬化门静脉高压患者的胆道运动功能，以３０例肝胆正常者作为对照。结累肝硬化门静脉高压患者胆囊排空延迟发生率为５２．５％，明显高于非肝病组的１０％（ｘ２＝１１．９２，Ｐ＜０．０１）；与非肝病者比较，胆肠通过时间明显延长，胆囊平均充盈速率显著减慢，胆囊排空指数显著降低（ｔ值分别为１１０８、２．９４、２．１０，Ｐ＜０．０５或Ｐ＜０．０１），并与肝功能分级有密切的关系。结论肝硬化门静脉高压常伴有胆道运动障碍，且与肝功能损伤程度有关。
Objedve To study binary motility in cirrhotic patients with portal hypertension and analyze the relationship between these biliary motility and the degree of liver function. Method Binary mohlity funchon was deteCted in 40 patients with portal hypertension and 30 normal controls by using quantitative hepatobiliary scinhgraphy. Results The rate of dysfunchon of gallbladder in cirrhotic patients was 52.5%, and it was significantly higher than that in controls (xo=l l.92, P < 0.01). Compared with the normal controls, the bile's transit in binary duct of cirrhohc patients was slower (t =l l.09, P < 0.01), the time of gallbladder visualization became longer(t = 5.65, P < 0.01), and the gallbladder emptying time was markedly prolonged (t=2.10, P < 0.05). A correlation was also seen between these binary motility and the degree of liver function. Conclusion Cirrhotic patients with portal hypertension of tell have abnormal motility of gallbladder and binary duct.
出处
《中华肝脏病杂志》
CAS
CSCD
2000年第1期35-36,共2页
Chinese Journal of Hepatology
关键词
肝硬化
门脉高压症
胆道运动功能
Liver cirrhosis
Hypertension, portal
Motion, binary
Radionuclide imaging
