摘要
炎症性肠病(IBD)的发病机制与免疫、炎症、损伤、遗传等因素密切相关。MicroRNAs是一类小的非编码RNA,其通过与靶基因3’UTR区结合,负向调控基因表达,在炎症性肠病的发病机制中发挥重要的作用。
The pathogenesis of IBD is associated with immune response,inflammation,injure and genetic factors.MicroRNAs are a class of short,noncoding RNAs that regulate gene expression by binding to the 3＇UTR of mRNA and cause translational inhibition which play an important role in the pathogenesis of IBD.
出处
《胃肠病学和肝病学杂志》
CAS
2012年第1期80-82,共3页
Chinese Journal of Gastroenterology and Hepatology
