摘要
目的筛查普通人群微量白蛋白尿（MAU）的患病率，并分析代谢综合征（MS）不同组分与MAU的关系。方法对进行体检的1654例健康人群测定身高、体重、血压、空腹血糖、血脂、尿微量白蛋白和肌酐等指标，分组统计MAU的患病率及与MS各组分的关系。结果MAU组年龄、体重指数、血压、空腹血糖和血脂水平均显著高于无MAU组。MAU在普通人群中的患病率为8．1％，随着年龄的增长，MAU的患病率有增高的趋势，60岁以后显著增高。各代谢异常组MAU的患病率显著增高，以MS组患病率最高，达20.7％。肥胖、高血压、高血糖、血脂紊乱和年龄是MAU发生的独立风险因素，御值分别为3．11、2．99、2．54、1．62、1.22。结论肥胖、高血压、高血糖、血脂紊乱和年龄是MAU发生的主要风险因素，对中老年人和代谢异常人群进行MAU的筛查是必要的。
Objective To investigate the prevalence of microalbuminuria （MAU） and its association with metabolic syn-drome （MS） in general population. Methods A total 1 654 subjects undergoing health check-up in Hangzhou city were selected by multistage,clustered complex sampling method. The fasting glucose, blood lipids, urinary albumin, urinary creatinine and an-thropometric indices were measured. The association of MAU with MS and its components were examined by univariate and multivariate logistic regression analysis. Results Subjects with MAU had higher age, BMI, blood pressure, fasting glucose and triglycerides levels than those without MAU. The prevalence of MAU in this population was 8.1%. The incidence of MAU was in- creased with the age. The prevalence of MAU increased in subjects with metabolic abnormalities and for those with metabolic syndrome the incidence of MAU was 20.7%. Obesity, hypertension, hyperglycemia, hyperlipidemia and age were independent risk factors for MAU in both genders, the odds ratios were 3.11, 2.99, 2.54, 1.62 and 1.22, respectively, Conclusion Obesity, high blood pressure, high blood lipids, high blood sugar and age are main risk factors causing MAU in general population.
出处
《浙江医学》
CAS
2011年第12期1753-1755,1798,共4页
Zhejiang Medical Journal
关键词
微量白蛋白尿
普通人群
患病率
代谢综合征
Microalbuminuria General population Prevalence Metabolic syndrome
