摘要
动物模型在研究食物过敏中发挥重要作用，该文讨论不同食物过敏动物模型的优缺点，包括动物种类和品系选择、实验致敏原选择、暴露途径和是否使用佐剂、过敏模型的评价指标等，为评估新型蛋白的变应原性与防治食物过敏提供理论依据。
Animal models play an important role in study on food allergy. This paper reviews the potential benefits and pitfalls of different animal models, including animal species and strains, test proteins, routes of exposure,the incorpration of adjuvants and evaluting indictor of allergic models, which can provide theoretical basis for evaluting the potential allergenicity of novel proteins and preventing food allergic diseases.
出处
《国际儿科学杂志》
2012年第1期68-70,共3页
International Journal of Pediatrics
关键词
食物过敏
动物模型
致敏原
佐剂
Food allergy
Animal models
Allergen
Adjuvants
