摘要
目的探讨吲哚氰绿清除试验与Child-Pugh肝功能分级在术前评估肝脏储备功能的价值。方法选择我院2009年10月至2011年2月期间的103例肝癌肝切除患者为对象,手术前测定ICG 15min潴留率(ICGR15),并评估肝纤维化百分比,对手术前、后肝功能进行Child-Pugh分级,分析三者之间的关系。结果随着肝功能级别的升高,肝纤维化百分比逐渐升高,在Child-Pugh A、B、C分级间两两比较差异有统计学意义(P<0.05)。ICGR15与肝纤维化百分比呈直线相关趋势(rs=0.960,P<0.05)。术后Child-Pugh分级由A级变为B级或由B级变为C级的患者术前ICGR15值均明显高于术前、术后Child-Pugh分级不变的患者(P<0.05)。结论联合ICGR15和Child-Pugh分级能提高术前对于肝脏储备功能评估的准确性。
Objective To investigate the effect of indocyanogen green retention rate（ICGR） measurement and Child-Pugh classification of liver function in the preoperative evaluation of hepatic functional reservation. Methods The level of ICGR at 15 min（ICGR15） and the percentage of liver fibrosis in 103 patients with liver cancer were measured before hepatectomy,and the Child-Pugh classification of liver function was evaluated before and after the operations,and their connections were analyzed. Results As the rise of Child-Pugh classification of liver function,the percentage of liver fibrosis increased gradually,there were significant differences between any two Child-Pugh classification（P〈0.05）.There was a linear correlation between the ICGR15 and the liver fibrosis percentage（rs=0.960,P〈0.05）.The value of preoperative ICGR15 in patients with postoperative Child-Pugh classification from grade A to grade B or grade B to grade C was gnificantly higher than that in patients with stabilization of Child-Pugh classification before and after operations（P〈0.05）. Conclusion ICGR15 combined with Child-Pugh classification can improve the accuracy for the evaluation of preoperative hepatic functional reservation. 更多
出处
《中国普外基础与临床杂志》
CAS
2011年第12期1314-1316,共3页
Chinese Journal of Bases and Clinics In General Surgery
