摘要
目的 探讨血清超敏C反应蛋白（hs-CRP）及CA72-4水平检测对胃癌患者手术治疗前后的临床意义.方法 选择80例受试者,其中胃癌患者40例,健康者40例.采用免疫比浊法检测血清hs-CRP及电化学发光免疫法检测CA72-4在胃癌患者手术治疗前后血清中的含量,并与健康对照组作对比.结果 手术前胃癌患者血清hs-CRP含量为35.90±15.69 mg/L,CA72-4含量为25.51±15.19 U/ml,均显著高于健康对照组,差异有统计学意义（t值为8.31,6.65,P〈0.01）.手术后血清中两指标含量与术前比较差异有统计学意义（t值为6.12,6.23,P〈0.01）.结论血清hs-CRP及CA72-4水平检测对评估胃癌患者手术治疗前后的病情及观察预后均有重要的临床价值.对比组之间的差异有统计学意义.
Objective To investigate the clinical significance of detecting serum high sensitivity C reactive protein （hs-CRP） and CA72 4 levels in patients with gastric cancer before and after surgical treatment. Methods 80 subjects,including 40 cases of gastric cancer patients and healthy people in 40 cases were chosen. The serum levels in gastric cancer patients before and after surgery were detected by detecting serum hs CRP with imnmne turbidimetry and by detecting CA72-4 with electro chemical luminescence immunoassay （ECLI）, compared with that of the healthy control group. Results Before surgery, serum hs-CRP concentration of gastric cancer patients was 35.90± 15. （39 mg/L,CA72-4 concentration was 25.51 ±15.19 U/ ml,and these figures were significantly higher than that of the control group with statistical significance （ t =8.31 or 6.65, P 〈0. 01 ）. Two indicators of serum after surgery,compared with preoperative levels, were statistically significant （ t=6.12 or 6.23, P〈0. 01）. Conclusion Serum hs-CRP detection and CA72-4 detection ware clinically important to assess the condition and observation of gastric cancer patients before and after surgical treatment. Differences between comparison groups ware statistically significant.
出处
《现代检验医学杂志》
CAS
2011年第6期138-139,共2页
Journal of Modern Laboratory Medicine
关键词
胃癌
超敏C反应蛋白
CA72-4
gastric cancer
high sensitivity C-reactive protein
CA72-4
